Industry Information Targeting mechanisms of tailed bacteriophages
Tailed phages use a broad range of receptor-binding proteins, such as tail fibres, tail spikes and the central tail spike, to target their cognate bacterial
Industry Information Dual-site recognition of Pseudomonas aeruginosa using polymyxin B
To overcome the poor binding specificity of polymyxin B, a recombinant bacteriophage tail fiber protein was expressed and employed as a species-specific recognition element for the target
Industry Information RBPseg: Toward a complete phage tail fiber structure atlas
RBPseg enables accurate modeling of tail fiber structure, providing the first comprehensive tail fiber structure atlas. INTRODUCTION Bacteriophages are the
Industry Information Dog Tail Anatomy
Learn dog tail anatomy with a labeled diagram. You will get the detailed anatomy of the dog tail bone, muscle, and artery with a diagram.
Industry Information Determination of the three-dimensional structure of bacteriophage Mu
In this study, we have determined the structure of the alternative tail fiber subunit, gp52, and compared it with other tail fibers. The results revealed that Mu phage employs different structural
Industry Information Major tail proteins of bacteriophages of the order Caudovirales
Finally, we summarize the structural elements of major tail proteins and conceptualize how different amounts of tail tube flexibility confer heterogeneity within cryo-EM maps and, thus, limit high
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Checking your browser before accessing pmc.ncbi m.nih.gov
Industry Information Asymmetric Structure of Podophage GP4 Reveals a Novel
In this study, we identified a new structure of the podophage with three types of tail fibers, and such phages with different types of fibers may have a broad host range and/or infect host cells
Industry Information Major tail proteins of bacteriophages of the order
Technological advances in cryo-EM in recent years have given rise to detailed atomic structures of bacteriophage tail tubes—a class of filamentous
Industry Information Assembly of bacteriophage T4 tail fibers: Identification and
Formation of both the tail fiber and the baseplate of bacteriophage T4 depends on the product of T4 gene 57. A single amber mutation in that gene causes loss of two T4-specific proteins. Their
Industry Information Attachment of tail fibers in bacteriophage T4 assembly: Role of the
Abstract The collar and whiskers of bacteriophage T4 extend outward from the top of the tail and play a role in regulating retraction of the tail fibers (Conley & Wood, 1975). The collar and
Industry Information Structures of the tailed bacteriophages that infect Gram-positive
Assembly of tail fibers from some bacteriophage requires the aid of an ''autochaperone'' as shown for the phi29 tail appendage . The precursor protein of the phi29 tail fiber contains an ATP
Industry Information Phage tail fibre assembly proteins employ a modular structure to drive
We find that Tfa proteins are comprised of two domains: a non-conserved N-terminal domain that binds to the C-terminal region of the fibre and a conserved C-terminal domain that
Industry Information The small genome, virulent, non-contractile tailed bacteriophages that
Their virions have isometric icosahedral heads in the 60–70 nm diameter range, and although their long noncontractile tails vary somewhat in length, width, flexibility and shape of the tail
Industry Information A Closer Look at a T4
Each fiber consists of about 5 or 6 protein units. In some electron micrographs these long fibers appear to be folded back along the tail sheath of untriggered phage particles. When a chance contact occurs
Industry Information Architecture of the bacteriophage lambda tail: Structure
To acquire atomic-level structural details, the tail particles were divided into three distinct reconstructions: tail cap, tail tip, and tail fiber (Figure 1 B).
Industry Information What are tail fibers and their role in phage infection?
Tail fibers are specialized protein appendages on bacteriophages that recognize and attach to specific bacterial host cell receptors, initiating viral infection.
Industry Information The tail structure of bacteriophage T4 and its mechanism of
Bacteriophage T4 consists of multiple copies of more than 40 different proteins that form its head, neck, tail and fibers. About 22 of these proteins form the T4 tail, including the tail tube
Industry Information RBPseg: Toward a complete phage tail fiber structure atlas
Here, we introduce RBPseg, a method that combines monomeric ESMFold predictions with a structural- based domain identi cation approach, to divide tail ber sequences into manageable fractions for high-
Industry Information RBPseg: Toward a complete phage tail fiber structure atlas
Using this approach, we generated complete tail fiber models, validated by single-particle cryo–electron microscopy of five fibers from three phages.
Industry Information Functional domains of Acinetobacter bacteriophage tail fibers
In this study, we analyzed the tail fibers of published Acinetobacter phages and identified different functional domains present. These data will enable further research and development on these
Industry Information The function of tail fibers in triggering baseplate expansion of
More fibers (a) increase the ability to attach to the cells and (b) increase the number of tail fiber attachment sites in the baseplate which are filled. In. order to distinguish between these two
Industry Information Assembly of bacteriophage T4 tail fibers: The sequence of gene
Intermediates in bacteriophage T4 tail fiber assembly, which accumulate in cells infected with mutants blocked at various stages of tail fiber formation, have been fractionated by velocity sedimentation and
Industry Information Towards a complete phage tail fiber structure atlas
To validate our approach, we used single-particle cryo-electron microscopy to analyze five tail fibers from three phages of the BASEL collection.
Industry Information Functional domains of Acinetobacter bacteriophage tail
The functional domains responsible for the capsule degradation activity are often found in the tail fibers of select A. baumannii phages.